Friday, December 16, 2011

GOP senators say Bernanke plans no Europe bailout (AP)

WASHINGTON ? Federal Reserve Chairman Ben Bernanke has assured Republican senators that the Fed does not intend to bail out Europe from its debt crisis, according to participants in the meeting Wednesday.

Sen. Lindsey Graham, R-S.C., said Bernanke told the group that he did not "have the intention or the authority" to provide bailout support to Europe.

Sen. Bob Corker, R-Tenn., said Bernanke had offered this assurance "multiple times" during the closed-door meeting, which lasted about an hour.

"I think people walked away knowing he has no intentions whatsoever of furthering U.S. involvement in the crisis," Corker told reporters.

Lawmakers in both parties have expressed sharp opposition to any U.S. support for Europe that might put taxpayer money at risk, especially after the uproar that followed the $700 billion bailout of U.S. financial institutions beginning in 2008.

Bernanke was invited to meet with GOP senators by Sen. Lamar Alexander of Tennessee, the chairman of the Senate Republican conference. The session came after a similar discussion Bernanke held with Senate Democrats on Oct. 20.

Senators said Bernanke told them that the Fed was studying developments in Europe and their possible impact on the U.S. economy.

"He's very concerned," Sen. Orin Hatch, R-Utah, told reporters. "He did say, if they can't get their fiscal situation under control, it could affect us. A collapse over there would be detrimental to us."

Fed policymakers held their final meeting of the year Tuesday. In a statement afterward, they portrayed the economy as slightly healthier despite risks from the European crisis. The Fed held off on any new steps to boost U.S. growth.

In its statement Tuesday, the Fed warned of risks to the economy from strains in global financial markets, a reference to Europe's problems

Source: http://us.rd.yahoo.com/dailynews/rss/economy/*http%3A//news.yahoo.com/s/ap/20111215/ap_on_bi_ge/us_bernanke_europe

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Wednesday, December 7, 2011

Steyn: Newt ???like Teddy Roosevelt mixed someone sort of novelty-crazed futurologist??? [VIDEO] (Daily Caller)

In an appearance on ?The Michael Berry Show? on KTRH in Houston on Tuesday, a disappointed Mark Steyn, the author of ?After America: Get Ready for Armageddon,? declared the 2012 Republican nominating process a failure and chalked up the proliferation of cable debates as a substitute for campaigning in the early primary states as the reason.

?I think the nomination process failed last time around when John McCain wound up as the nominee and I think it is heading for failure this time around,? Steyn said. ?I?m speaking to you from my home in New Hampshire ? but in my state of New Hampshire, one reason we like the primaries is its all supposed to be about swinging by local diners and county fairs, and the annual pancake breakfast and all this kind of thing. And we know the clich?s ? the woman who tells the Washington Post, the New York Times every four years, you know, ?I won?t vote for any candidate I haven?t danced with at least three times.??

?None of that happened this time around,? he continued. ?Instead, we had some new TV debate every 48 hours ?sometimes on cable channels none of us ever heard of until they hosted a debate ? and the result is there has been no retail politics. And Newt Gingrich, brilliantly in my view ? who would have been terrible at the whole shaking hands at the diner and all that kind of stuff ? through the debates has emerged as the front-runner.?

Listen:

Tuesday, December 6, 2011

comScore: 38 Percent Of Smartphone Owners Have Used A Mobile Device To Make A Purchase

Mobile ShoppingMobile shopping is undoubtedly on the rise, and today comScore is releasing new data reinforcing this continuing trend. According to the data research and analysis firm, 38 percent of smartphone owners have used their phone to make a purchase at least once in the course of their device ownership. The most popular products purchased on smartphones during the month of September included digital goods, clothing/accessories, tickets and daily deals. In September, two-thirds of all smartphone owners performed some sort of shopping activity on their phones, including comparing products and prices, searching for coupons, taking product pictures or locating a retail store.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/bPkgbngGvYM/

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Some Asians' college strategy: Don't check `Asian' (AP)

Lanya Olmstead was born in Florida to a mother who immigrated from Taiwan and an American father of Norwegian ancestry. Ethnically, she considers herself half Taiwanese and half Norwegian. But when applying to Harvard, Olmstead checked only one box for her race: white.

"I didn't want to put `Asian' down," Olmstead says, "because my mom told me there's discrimination against Asians in the application process."

For years, many Asian-Americans have been convinced that it's harder for them to gain admission to the nation's top colleges.

Studies show that Asian-Americans meet these colleges' admissions standards far out of proportion to their 6 percent representation in the U.S. population, and that they often need test scores hundreds of points higher than applicants from other ethnic groups to have an equal chance of admission. Critics say these numbers, along with the fact that some top colleges with race-blind admissions have double the Asian percentage of Ivy League schools, prove the existence of discrimination.

The way it works, the critics believe, is that Asian-Americans are evaluated not as individuals, but against the thousands of other ultra-achieving Asians who are stereotyped as boring academic robots.

Now, an unknown number of students are responding to this concern by declining to identify themselves as Asian on their applications.

For those with only one Asian parent, whose names don't give away their heritage, that decision can be relatively easy. Harder are the questions that it raises: What's behind the admissions difficulties? What, exactly, is an Asian-American ? and is being one a choice?

Olmstead is a freshman at Harvard and a member of HAPA, the Half-Asian People's Association. In high school she had a perfect 4.0 grade-point average and scored 2150 out of a possible 2400 on the SAT, which she calls "pretty low."

College applications ask for parent information, so Olmstead knows that admissions officers could figure out a student's background that way. She did write in the word "multiracial" on her own application.

Still, she would advise students with one Asian parent to "check whatever race is not Asian."

"Not to really generalize, but a lot of Asians, they have perfect SATs, perfect GPAs, ... so it's hard to let them all in," Olmstead says.

Amalia Halikias is a Yale freshman whose mother was born in America to Chinese immigrants; her father is a Greek immigrant. She also checked only the "white" box on her application.

"As someone who was applying with relatively strong scores, I didn't want to be grouped into that stereotype," Halikias says. "I didn't want to be written off as one of the 1.4 billion Asians that were applying."

Her mother was "extremely encouraging" of that decision, Halikias says, even though she places a high value on preserving their Chinese heritage.

"Asian-American is more a scale or a gradient than a discrete combination . I think it's a choice," Halikias says.

But leaving the Asian box blank felt wrong to Jodi Balfe, a Harvard freshman who was born in Korea and came here at age 3 with her Korean mother and white American father. She checked the box against the advice of her high school guidance counselor, teachers and friends.

"I felt very uncomfortable with the idea of trying to hide half of my ethnic background," Balfe says. "It's been a major influence on how I developed as a person. It felt like selling out, like selling too much of my soul."

"I thought admission wouldn't be worth it. It would be like only half of me was accepted."

Other students, however, feel no conflict between a strong Asian identity and their response to what they believe is injustice.

"If you know you're going to be discriminated against, it's absolutely justifiable to not check the Asian box," says Halikias.

Immigration from Asian countries was heavily restricted until laws were changed in 1965. When the gates finally opened, many Asian arrivals were well-educated, endured hardships to secure more opportunities for their families, and were determined to seize the American dream through effort and education.

These immigrants, and their descendants, often demanded that children work as hard as humanly possible to achieve. Parental respect is paramount in Asian culture, so many children have obeyed ? and excelled.

"Chinese parents can order their kids to get straight As. Western parents can only ask their kids to try their best," wrote Amy Chua, only half tongue-in-cheek, in her recent best-selling book "Battle Hymn of the Tiger Mother."

"Chinese parents can say, `You're lazy. All your classmates are getting ahead of you,'" Chua wrote. "By contrast, Western parents have to struggle with their own conflicted feelings about achievement, and try to persuade themselves that they're not disappointed about how their kids turned out."

Of course, not all Asian-Americans fit this stereotype. They are not always obedient hard workers who get top marks. Some embrace American rather than Asian culture. Their economic status, ancestral countries and customs vary, and their forebears may have been rich or poor.

But compared with American society in general, Asian-Americans have developed a much stronger emphasis on intense academic preparation as a path to a handful of the very best schools.

"The whole Tiger Mom stereotype is grounded in truth," says Tao Tao Holmes, a Yale sophomore with a Chinese-born mother and white American father. She did not check "Asian" on her application.

"My math scores aren't high enough for the Asian box," she says. "I say it jokingly, but there is the underlying sentiment of, if I had emphasized myself as Asian, I would have (been expected to) excel more in stereotypically Asian-dominated subjects."

"I was definitely held to a different standard (by my mom), and to different standards than my friends," Holmes says. She sees the same rigorous academic focus among many other students with immigrant parents, even non-Asian ones.

Does Holmes think children of American parents are generally spoiled and lazy by comparison? "That's essentially what I'm trying to say."

Asian students have higher average SAT scores than any other group, including whites. A study by Princeton sociologist Thomas Espenshade examined applicants to top colleges from 1997, when the maximum SAT score was 1600 (today it's 2400). Espenshade found that Asian-Americans needed a 1550 SAT to have an equal chance of getting into an elite college as white students with a 1410 or black students with an 1100.

Top schools that don't ask about race in admissions process have very high percentages of Asian students. The California Institute of Technology, a private school that chooses not to consider race, is about one-third Asian. (Thirteen percent of California residents have Asian heritage.) The University of California-Berkeley, which is forbidden by state law to consider race in admissions, is more than 40 percent Asian ? up from about 20 percent before the law was passed.

Steven Hsu, a physics professor at the University of Oregon and a vocal critic of current admissions policies, says there is a clear statistical case that discrimination exists.

"The actual dynamics of how it happens are really quite subtle," he says, mentioning factors like horse-trading among admissions officers for their favorite candidates.

Also, "when Asians are the largest group on campus, I can easily imagine a fund-raiser saying, `This is jarring to our alumni,'" Hsu says. Noting that most Ivy League schools have roughly the same percentage of Asians, he wonders if "that's the maximum number where diversity is still good, and it's not, `we're being overwhelmed by the yellow horde.'"

Yale, Harvard, Princeton and the University of Pennsylvania declined to make admissions officers available for interviews for this story.

Kara Miller helped review applications for Yale as an admissions office reader, and participated in meetings where admissions decisions were made. She says it often felt like Asians were held to a higher standard.

"Asian kids know that when you look at the average SAT for the school, they need to add 50 or 100 to it. If you're Asian, that's what you'll need to get in," says Miller, now an English professor at the University of Massachusetts-Dartmouth.

Highly selective colleges do use much more than SAT scores and grades to evaluate applicants. Other important factors include extracurricular activities, community service, leadership, maturity, engagement in learning, and overcoming adversity.

Admissions preferences are sometimes given to the children of alumni, the wealthy and celebrities, which is an overwhelmingly white group. Recruited athletes get breaks. Since the top colleges say diversity is crucial to a world-class education, African-Americans, Latinos, Native Americans, and Hawaiian/Pacific Islanders also may get in despite lower scores than other applicants.

A college like Yale "could fill their entire freshman class twice over with qualified Asian students or white students or valedictorians," says Rosita Fernandez-Rojo, a former college admissions officer who is now director of college counseling at Rye Country Day School outside of New York City.

But applicants are not ranked by results of a qualifications test, she says ? "it's a selection process."

"People are always looking for reasons they didn't get in," she continues. "You can't always know what those reasons are. Sometimes during the admissions process they say, `There's nothing wrong with that kid. We just don't have room.'"

In the end, elite colleges often don't have room for Asian students with outstanding scores and grades.

That's one reason why Harvard freshman Heather Pickerell, born in Hong Kong to a Taiwanese mother and American father, refused to check any race box on her application.

"I figured it might help my chances of getting in," she says. "But I figured if Harvard wouldn't take me for refusing to list my ethnicity, then maybe I shouldn't go there."

She considers drawing lines between different ethnic groups a form of racism ? and says her ethnic identity depends on where she is.

"In America, I identify more as Asian, having grown up there, and actually being Asian, and having grown up in an Asian family," she says. "But when I'm back in Hong Kong I feel more American, because everyone there is more Asian than I am."

Holmes, the Yale sophomore with the Chinese-born mother, also has problems fitting herself into the Asian box ? "it doesn't make sense to me."

"I feel like an American," she says, "...an Asian person who grew up in America."

Susanna Koetter, a Yale junior with an American father and Korean mother, was adamant about identifying her Asian side on her application. Yet she calls herself "not fully Asian-American. I'm mixed Asian-American. When I go to Korea, I'm like, blatantly white."

And yet, asked whether she would have considered leaving the Asian box blank, she says: "That would be messed up. I'm not white."

"Identity is very malleable," says Jasmine Zhuang, a Yale junior whose parents were both born in Taiwan.

She didn't check the box, even though her last name is a giveaway and her essay was about Asian-American identity.

"Looking back I don't agree with what I did," Zhuang says. "It was more like a symbolic action for me, to rebel against the higher standard placed on Asian-American applicants."

"There's no way someone's race can automatically tell you something about them, or represent who they are to an admissions committee," Zhuang says. "Using race by itself is extremely dangerous."

Hsu, the physics professor, says that if the current admissions policies continue, it will become more common for Asian students to avoid identifying themselves as such, and schools will have to react.

"They'll have to decide: A half-Asian kid, what is that? I don't think they really know."

The lines are already blurred at Yale, where almost 26,000 students applied for the current freshman class, according to the school's web site.

About 1,300 students were admitted. Twenty percent of them marked the Asian-American box on their applications; 15 percent of freshmen marked two or more ethnicities.

Ten percent of Yale's freshmen class did not check a single box.

___

Jesse Washington covers race and ethnicity for The Associated Press. He is reachable at http://www.twitter.com/jessewashington or jwashington(at)ap.org.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20111203/ap_on_re_us/us_i_m_not_asian

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Monday, December 5, 2011

Egypt vote: Highest turnout 'since the pharaohs'

Anticipating a strong presence in the new Egyptian parliament, ultraconservative Islamists outlined plans Friday for a strict brand of religious law, a move that could limit personal freedoms and steer a key U.S. ally toward an Islamic state.

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Egypt's election commission announced only a trickle of results from the first round of of country's first free vote in six decades and said 62 percent of eligible voters cast ballots in the highest turnout in modern history.

However, leaked counts point to a clear majority for Islamist parties at the expense of liberal activist groups that led the uprising against Hosni Mubarak, toppling a regime long seen as a secular bulwark in the Middle East.

The more pragmatic Muslim Brotherhood is poised to take the largest share of votes, as much as 45 percent. But the Nour Party, which espouses a strict interpretation of Islam in which democracy is subordinate to the Quran, could win a quarter of the house, giving it much power to affect debate.

Moderate Islamists have won elections in Tunisia and Morocco in the past two months.

The world is watching the election for pointers to the future in Egypt, the most populous Arab nation and one hitherto seen as a firm U.S. ally committed to preserving its peace treaty with Israel and fighting Islamist militancy.

Abdul Moez Ibrahim, the head of the election committee, joked that the turnout was the highest in any Egyptian election "since the pharaohs." It was even greater than in the "forgeries of the past elections," he added, referring to the Mubarak era.

Story: Islamist parties poised for big win in Egypt

He said 8.3 million of 13.6 million registered voters in areas that voted in the first round had cast their ballots. Other parts of the country will vote in two more rounds, and run-offs must also be held in a six-week election process.

"The blood of martyrs has watered the tree of freedom, social justice and the rule of law. We are now reaping its first fruits," Ibrahim said in tribute to more than 850 people killed in a popular revolt that toppled Mubarak in February.

Protesters were out again in Cairo's Tahrir Square Friday to mourn 42 people killed in the 10 days before the vote at rallies demanding the generals who replaced Mubarak give way to civilian rule.

"Without Tahrir, we wouldn't have had these elections," said Mohamed Gad in the square that cradled the revolt. "God willing, the elections will succeed and the revolution will triumph."

But many of the young people who took to the streets early this year now fear their revolution risks being stolen, either by the army rulers or by well-organized Islamist parties.

Conservatism could wreck tourism
Ibrahim announced the results of only a handful of clear-cut victories for individual candidates, with most going to run-offs next week, and gave no figures for party lists in the polls.

He said four candidates, two from the Brotherhood's Freedom and Justice Party (FJP) and two liberals, won over 50 percent of votes for outright victory out of 56 individual seats at stake.

The FJP said 39 of its candidates would fight run-off races. The party dominates a coalition with other smaller parties. Their coalition will be contesting 45 seats.

Yousry Hamad, a senior official of the Salafi Nour Party, said 26 of its contenders were involved in run-offs, 24 of them going head-to-head with FJP candidates.

Muslim Brotherhood bends rules to win big in Egypt

"We will go into the run-offs with all our might and there will be no deals with anyone. We will aim to do better than we have already," Nour leader Emad Abdel Ghafour told Reuters.

In Egypt's complex election process, two-thirds of the 498 seats will go proportionately to party lists, with the rest to individual candidates.

The Muslim Brotherhood, banned but semi-tolerated under Mubarak, has said its FJP expects to win 43 percent of party list votes in the first stage, building on the Islamist group's decades of grassroots social and religious work.

But the Brotherhood's website also forecast that the Salafi al-Nour party would gain 30 percent of the vote, a shock for some Egyptians, especially minority Christian Copts, who fear it will try to impose strict Islamic codes on society.

Nour said Thursday it expected 20 percent of the vote.

PhotoBlog: 'Massive' turnout in Egyptian elections

As in Saudi Arabia, Salafis want to bar women and Christians from executive posts. They would also ban alcohol, mixed beach bathing and "un-Islamic" art and literature.

Such curbs would wreck Egypt's vital tourism industry, which employs about one in eight of the workforce.

More secular-minded Egyptian parties, some of which were only formed after Mubarak's fall, had always feared that they would not have enough time to put up a credible challenge to their experienced and better-funded Islamist rivals.

The liberal multi-party Egyptian Bloc has said it is on track to secure about a fifth of votes for party lists.

Ibrahim, the election chief, acknowledged several violations in Monday and Tuesday's voting, notably campaigning outside polling stations, long queues, failure to stamp some ballots, and late arrival of ballot papers and of a few of the supervising judges. He said these did not affect the results.

Promise of civilian rule
Egypt's ruling generals, who have promised civilian rule by July, have said they will keep powers to appoint or fire a cabinet even after an elected parliament is installed.

Story: Egypt's military takes credit for 1st election turnout

The United States, which still gives Egypt about $1.3 billion a year in mostly military aid, has urged the ruling generals to step aside swiftly and make way for civilian rule.

The leader of the Brotherhood's FJP appeared to set the stage for a political tussle with the military this week by saying the majority in parliament should form the government, but the party later said it was premature to discuss the issue.

The FJP says its priorities are ending corruption, reviving the economy and establishing a true democracy in Egypt.

Ever pragmatic, the Brotherhood may avoid allying with Salafis in parliament and seek more moderate coalition partners to reassure Egyptians and foreigners of its intentions.

Senior FJP official Essam el-Erian said before the vote that

Salafis, who had kept a low profile and shunned politics during Mubarak's 30-year rule, would be "a burden for any coalition."

Kamal al-Ganzouri, asked by the army to form a "national salvation government," aims to complete it soon. State television said the cabinet was still being formed, but included at least half of the outgoing team.

Protesters in Tahrir have rejected Ganzouri, 78.

"It is unacceptable that after the revolution, an old man comes and governs. We don't want the army council anymore. they should go back to barracks," said Menatallah Abdel Meguid, 24.

Reuters and The Associated Press contributed to this report.

Source: http://www.msnbc.msn.com/id/45533234/ns/world_news-mideast_n_africa/

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Sunday, December 4, 2011

Microscopic cells race to victory in first World Cell Race at ASCB meeting

Microscopic cells race to victory in first World Cell Race at ASCB meeting [ Back to EurekAlert! ] Public release date: 3-Dec-2011
[ | E-mail | Share Share ]

Contact: John Fleischman
jfleischman@ascb.org
513-706-0212
American Society for Cell Biology

World Cell Race pulls 70 entries for title of world's fastest cell

DENVER, CO, December 3, 2011--A "team" of fast-moving, bone marrow stem cells from a research laboratory in Singapore has run away with the first World Cell Race, finishing first with a cellular speed record of 5.2 microns per minute (or 0.000204 inches per minute) in results announced today at the 51st Annual Meeting of the American Society for Cell Biology (ASCB).

The mesenchymal bone marrow stem cells grown at the National University of Singapore by Yuchun Liu, PhD, were one of 70 cell lines entered by labs from all over the world and raced on specially designed micro-tracks, a few microns wide and 400 microns long. The micro-tracks, donated by CYTOO Cell Architects of Grenoble, France, were coated with fibronectin, a natural substrate on which the cells could get traction. The racing cell lines were frozen for shipment to one of six labs around the globe where they were thawed, stained with fluorescent dyes, and raced against the clock. The action was video recorded for 24 hours and the times were sorted by custom software created at the Institut Curie in Paris, according to Manuel Thry, PhD, who along with Ana-Maria Lennon-Dumnil, PhD, and Matthieu Piel, PhD, organized the World Cell Race. Piel and Lennon-Dumnil are at the Institut Curie. Thry is with the Institut de Recherche en Technologies et Sciences pour le Vivant (iRTSV) in Grenoble, France. The institute is part of the Commissariat l'Energie Atomique (CEA).

"We measured the position and speeds of all individual cells in each group," says Thry. "For each cell line, we then determined the fastest run over 400 microns."

Thry says the idea for a cell race came to them at last year's ASCB Annual Meeting in Philadelphia where the three French scientists were struck by the large number of papers and the lively discussions about cell migration. How cells move is one of the hottest fields in research today because of the implications in cancer where motilitythe ability of tumor cells to move autonomously--is critical to understanding how cancer metastasizes. Cell movement is also vital to normal biology including embryonic development and human growth. Thry says that the World Cell Race was a way to mix the fun of a scientific sporting event with serious research into how speed reflects the nature of certain cells.

The results of the race were announced in Denver as the climax of an ASCB Special Interest Subgroup titled, "Mechanisms for Rapid Cell Migration." More information on cell mobility can be found at: http://www.ascb.org/meetings/subgroup/subgroup.cfm#I

Finishing second and third place were cell lines provided by Odile Filhol-Cochet, PhD, of iRTSV/CEA in France. The second place winners were "wild type" normal mammary breast epithelial cells, clocked along the 400 micron track at 3.2 microns per minute. Third place award went to a cell culture of these mammary epithelial cells altered in the lab with a knocked-down casein kinase 2 and an overactive Ras pathway. The re-engineered cells roared down the track at 2.7 microns per minute.

In fourth place were human keratinocytes cultured from samples taken from patients suffering from Kindler syndrome, a rare genetic skin disorder, entered by Rumena Begum of King's College London, UK. Their speed over 400 microns was 2.5 microns per minute.

The winners will receive a Nikon camera and a World Cell Race medal.

In addition to being enjoyable, the first World Cell Race generated valuable data. "Data analysis revealed an unknown feature of cell migration," says Thry. "Fast cells were persistent?they rarely changed the direction of their migration. Slow cells were not persistent. They went back and forth." Correlating the speed of cells to their invasive behavior in cancer, for example, could uncover new approaches to treatment, Thry believes.

If the First World Cell Race is a success at ASCB, Thry hopes for a second running next year. "Maybe with additional games," he suggests. "Swimming and weightlifting."

###

Media contacts:
John Fleischman
ASCB Science Writer
513-706-0212
jfleischman@ascb.org

Cathy Yarbrough
ASCB Media Coordinator
858-243-1814
cyarbrough@ascb.org

In Denver, December 3-7, 2001
ASCB Newsroom, Room 204
Colorado Convention Center
303-228-8380

Manuel Thry
manuel.thery@cea.fr
(33) 6 6204 2122
http://www.worldcellrace.com/


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Microscopic cells race to victory in first World Cell Race at ASCB meeting [ Back to EurekAlert! ] Public release date: 3-Dec-2011
[ | E-mail | Share Share ]

Contact: John Fleischman
jfleischman@ascb.org
513-706-0212
American Society for Cell Biology

World Cell Race pulls 70 entries for title of world's fastest cell

DENVER, CO, December 3, 2011--A "team" of fast-moving, bone marrow stem cells from a research laboratory in Singapore has run away with the first World Cell Race, finishing first with a cellular speed record of 5.2 microns per minute (or 0.000204 inches per minute) in results announced today at the 51st Annual Meeting of the American Society for Cell Biology (ASCB).

The mesenchymal bone marrow stem cells grown at the National University of Singapore by Yuchun Liu, PhD, were one of 70 cell lines entered by labs from all over the world and raced on specially designed micro-tracks, a few microns wide and 400 microns long. The micro-tracks, donated by CYTOO Cell Architects of Grenoble, France, were coated with fibronectin, a natural substrate on which the cells could get traction. The racing cell lines were frozen for shipment to one of six labs around the globe where they were thawed, stained with fluorescent dyes, and raced against the clock. The action was video recorded for 24 hours and the times were sorted by custom software created at the Institut Curie in Paris, according to Manuel Thry, PhD, who along with Ana-Maria Lennon-Dumnil, PhD, and Matthieu Piel, PhD, organized the World Cell Race. Piel and Lennon-Dumnil are at the Institut Curie. Thry is with the Institut de Recherche en Technologies et Sciences pour le Vivant (iRTSV) in Grenoble, France. The institute is part of the Commissariat l'Energie Atomique (CEA).

"We measured the position and speeds of all individual cells in each group," says Thry. "For each cell line, we then determined the fastest run over 400 microns."

Thry says the idea for a cell race came to them at last year's ASCB Annual Meeting in Philadelphia where the three French scientists were struck by the large number of papers and the lively discussions about cell migration. How cells move is one of the hottest fields in research today because of the implications in cancer where motilitythe ability of tumor cells to move autonomously--is critical to understanding how cancer metastasizes. Cell movement is also vital to normal biology including embryonic development and human growth. Thry says that the World Cell Race was a way to mix the fun of a scientific sporting event with serious research into how speed reflects the nature of certain cells.

The results of the race were announced in Denver as the climax of an ASCB Special Interest Subgroup titled, "Mechanisms for Rapid Cell Migration." More information on cell mobility can be found at: http://www.ascb.org/meetings/subgroup/subgroup.cfm#I

Finishing second and third place were cell lines provided by Odile Filhol-Cochet, PhD, of iRTSV/CEA in France. The second place winners were "wild type" normal mammary breast epithelial cells, clocked along the 400 micron track at 3.2 microns per minute. Third place award went to a cell culture of these mammary epithelial cells altered in the lab with a knocked-down casein kinase 2 and an overactive Ras pathway. The re-engineered cells roared down the track at 2.7 microns per minute.

In fourth place were human keratinocytes cultured from samples taken from patients suffering from Kindler syndrome, a rare genetic skin disorder, entered by Rumena Begum of King's College London, UK. Their speed over 400 microns was 2.5 microns per minute.

The winners will receive a Nikon camera and a World Cell Race medal.

In addition to being enjoyable, the first World Cell Race generated valuable data. "Data analysis revealed an unknown feature of cell migration," says Thry. "Fast cells were persistent?they rarely changed the direction of their migration. Slow cells were not persistent. They went back and forth." Correlating the speed of cells to their invasive behavior in cancer, for example, could uncover new approaches to treatment, Thry believes.

If the First World Cell Race is a success at ASCB, Thry hopes for a second running next year. "Maybe with additional games," he suggests. "Swimming and weightlifting."

###

Media contacts:
John Fleischman
ASCB Science Writer
513-706-0212
jfleischman@ascb.org

Cathy Yarbrough
ASCB Media Coordinator
858-243-1814
cyarbrough@ascb.org

In Denver, December 3-7, 2001
ASCB Newsroom, Room 204
Colorado Convention Center
303-228-8380

Manuel Thry
manuel.thery@cea.fr
(33) 6 6204 2122
http://www.worldcellrace.com/


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2011-12/asfc-mcr120111.php

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Saturday, December 3, 2011

Health gap has grown among young US adults, study finds

Health gap has grown among young US adults, study finds [ Back to EurekAlert! ] Public release date: 1-Dec-2011
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Contact: Hui Zheng
Zheng.64@sociology.osu.edu
614-688-8348
Ohio State University

COLUMBUS, Ohio -- Levels of health disparity have increased substantially for people born in the United States after 1980, according to new research.

The study also found that health disparity tends to increase as people move into middle age, before declining as people reach old age.

These two results suggest that the gap between the healthiest and least healthy people in the United States as a whole will grow larger for the next one or even two decades as the younger generations grow older and replace previous generations.

"As young people today reach middle age and preceding cohorts with a smaller health gap die off, we expect health disparities in the whole population to grow even larger," said Hui Zheng, lead author of the study and assistant professor of sociology at Ohio State University.

A lot will depend on whether future generations will continue the trend, seen in post-baby boomers, of large health disparities.

"If that trend continues, as I expect it will, health disparities in the whole population will increase in the coming decades," Zheng said.

The health gap has not always been growing, according to the study. Health disparities continuously declined from those born early in the 20th century to the baby boomer cohort, before increasing for post-baby boomer cohorts, especially those born after 1980.

Zheng conducted the study with Yang Yang of the University of North Carolina-Chapel Hill and Kenneth Land of Duke University. Their results appear in the December issue of the journal American Sociological Review.

This study provides one of the clearest, most comprehensive pictures ever of health disparities in the United States because of a methodological innovation, Zheng said.

Zheng and his colleagues combined two statistical models that allowed them, for the first time, to disentangle how health disparity over time is affected by three factors: people's age, when they were born, and the time period when their health is assessed.

"We have never before been able to look at all three of these factors together and see how each interacts with the others to affect changes in health disparities," Zheng said.

The study is based on data from the National Health Interview Survey for the 24-year period from 1984 to 2007. The survey, which includes about 30,000 people each year, is conducted by the National Center for Health Statistics.

The survey asked respondents to rate their own health on a five-point scale from poor to excellent. While this is a self-report and not based on any objective health data, previous studies have shown that self-reported health is a good indicator of objective health and is actually better at predicting mortality among the elderly than doctor assessments, Zheng said.

The researchers took into account a variety of other factors that may affect health, including gender, race, marital status, work status, education and income.

Overall, the study found that late baby boomers those born from 1955 to 1964 reported better health than any other generation. In addition, self-rated health has significantly declined since the late 1990s.

One of the key findings was the large gap in self-reported health that opened up for people born since 1980. That means people are more spread out among the five health categories, from excellent to poor, Zheng said.

This data can't explain why health disparities grew, but research by other sociologists provides potential explanations, Zheng said.

For one, income inequality increased dramatically in the past three decades in the United States, which could impact accessibility to health care and other important resources.

Also, an increase in immigrants, both documented and undocumented, has probably changed the distribution of health ratings in the country, while the growing obesity crisis has added to those in poor health.

Finally, a growing "digital divide" in access to medical and health information on the internet has created disparities in health knowledge among different populations, which can affect health choices and outcomes.

The main reason that health disparity is expected to grow in the whole population in the coming decades has to do with what is happening among young adults born since 1980, Zheng said.

Current young adults have a larger health gap than preceding cohorts and, in addition, disparity rises as people move from youth to middle age, peaking at about age 55. Disparity then declines among the elderly, according to the study.

Those two factors will work together to increase disparity in the whole population as young adults replace their elders in the population.

Most young people are generally healthy, which keeps disparities low, Zheng said. As people age and some develop health problems and diseases, disparity grows. But these disparities fall again in old age as sicker people die and only the healthier people remain. The narrower disparities in old age may also result from the fact that all older people suffer frailty and tend to share the same health risk factors. Another factor may be equalization of health care usage and protections through Medicare coverage after age 65.

The study also found gender differences in health across the lifespan. There is a relatively large gap in early adulthood, with men being healthier than women. This gap narrows until about age 61, as men are more likely to experience more severe forms of chronic conditions, such as heart disease.

The gap widens again after age 61, as only the healthier men survive and there is a relatively larger share of women with poorer health alive at older ages.

While this study focused on health, Zheng said this new model can be used to study other types of inequality, such as income, education or wealth.

"This model provides a powerful framework to identify and study the evolution of inequalities across age, period and cohorts," Zheng said.

###

Contact: Hui Zheng, (614) 688-8348; Zheng.64@sociology.osu.edu
Written by Jeff Grabmeier, (614) 292-8457; Grabmeier.1@osu.edu


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Health gap has grown among young US adults, study finds [ Back to EurekAlert! ] Public release date: 1-Dec-2011
[ | E-mail | Share Share ]

Contact: Hui Zheng
Zheng.64@sociology.osu.edu
614-688-8348
Ohio State University

COLUMBUS, Ohio -- Levels of health disparity have increased substantially for people born in the United States after 1980, according to new research.

The study also found that health disparity tends to increase as people move into middle age, before declining as people reach old age.

These two results suggest that the gap between the healthiest and least healthy people in the United States as a whole will grow larger for the next one or even two decades as the younger generations grow older and replace previous generations.

"As young people today reach middle age and preceding cohorts with a smaller health gap die off, we expect health disparities in the whole population to grow even larger," said Hui Zheng, lead author of the study and assistant professor of sociology at Ohio State University.

A lot will depend on whether future generations will continue the trend, seen in post-baby boomers, of large health disparities.

"If that trend continues, as I expect it will, health disparities in the whole population will increase in the coming decades," Zheng said.

The health gap has not always been growing, according to the study. Health disparities continuously declined from those born early in the 20th century to the baby boomer cohort, before increasing for post-baby boomer cohorts, especially those born after 1980.

Zheng conducted the study with Yang Yang of the University of North Carolina-Chapel Hill and Kenneth Land of Duke University. Their results appear in the December issue of the journal American Sociological Review.

This study provides one of the clearest, most comprehensive pictures ever of health disparities in the United States because of a methodological innovation, Zheng said.

Zheng and his colleagues combined two statistical models that allowed them, for the first time, to disentangle how health disparity over time is affected by three factors: people's age, when they were born, and the time period when their health is assessed.

"We have never before been able to look at all three of these factors together and see how each interacts with the others to affect changes in health disparities," Zheng said.

The study is based on data from the National Health Interview Survey for the 24-year period from 1984 to 2007. The survey, which includes about 30,000 people each year, is conducted by the National Center for Health Statistics.

The survey asked respondents to rate their own health on a five-point scale from poor to excellent. While this is a self-report and not based on any objective health data, previous studies have shown that self-reported health is a good indicator of objective health and is actually better at predicting mortality among the elderly than doctor assessments, Zheng said.

The researchers took into account a variety of other factors that may affect health, including gender, race, marital status, work status, education and income.

Overall, the study found that late baby boomers those born from 1955 to 1964 reported better health than any other generation. In addition, self-rated health has significantly declined since the late 1990s.

One of the key findings was the large gap in self-reported health that opened up for people born since 1980. That means people are more spread out among the five health categories, from excellent to poor, Zheng said.

This data can't explain why health disparities grew, but research by other sociologists provides potential explanations, Zheng said.

For one, income inequality increased dramatically in the past three decades in the United States, which could impact accessibility to health care and other important resources.

Also, an increase in immigrants, both documented and undocumented, has probably changed the distribution of health ratings in the country, while the growing obesity crisis has added to those in poor health.

Finally, a growing "digital divide" in access to medical and health information on the internet has created disparities in health knowledge among different populations, which can affect health choices and outcomes.

The main reason that health disparity is expected to grow in the whole population in the coming decades has to do with what is happening among young adults born since 1980, Zheng said.

Current young adults have a larger health gap than preceding cohorts and, in addition, disparity rises as people move from youth to middle age, peaking at about age 55. Disparity then declines among the elderly, according to the study.

Those two factors will work together to increase disparity in the whole population as young adults replace their elders in the population.

Most young people are generally healthy, which keeps disparities low, Zheng said. As people age and some develop health problems and diseases, disparity grows. But these disparities fall again in old age as sicker people die and only the healthier people remain. The narrower disparities in old age may also result from the fact that all older people suffer frailty and tend to share the same health risk factors. Another factor may be equalization of health care usage and protections through Medicare coverage after age 65.

The study also found gender differences in health across the lifespan. There is a relatively large gap in early adulthood, with men being healthier than women. This gap narrows until about age 61, as men are more likely to experience more severe forms of chronic conditions, such as heart disease.

The gap widens again after age 61, as only the healthier men survive and there is a relatively larger share of women with poorer health alive at older ages.

While this study focused on health, Zheng said this new model can be used to study other types of inequality, such as income, education or wealth.

"This model provides a powerful framework to identify and study the evolution of inequalities across age, period and cohorts," Zheng said.

###

Contact: Hui Zheng, (614) 688-8348; Zheng.64@sociology.osu.edu
Written by Jeff Grabmeier, (614) 292-8457; Grabmeier.1@osu.edu


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2011-12/osu-hgh112811.php

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